胃肠道间质瘤的MSCT表现与病理危险程度分级的关系

Relationship between MSCT findings and risk assessment of gastrointestinal stromal tumor

目的:探讨胃肠道间质瘤(GIST)的MSCT表现与病理危险程度分级的关系。方法:回顾性分析48例经手术、病理及免疫组化证实的GIST患者的MSCT表现,分析肿瘤的最大径、部位、生长方式、形状、实性成分密度与强化程度,以及Ki-67增殖指数与病理危险程度分级之间关系。结果:48例中,发生在胃部18例,肠道23例,胃肠道外7例;病理分级:低度危险9例,中度危险7例,高度危险32例。不同危险程度分级肿瘤的发生部位及实性部分强化程度差异均无统计学意义(均P> 0.05),肿瘤最大径、生长方式、实性成分密度、形态及是否发生转移差异均有统计学意义(均P<0.05),Ki-67增殖指数差异有统计学意义(P<0.05)。结论:GIST的MSCT表现具有一定特征性,且与病理危险程度分级具有密切关系,对GIST的诊断、临床治疗方案制订、判断预后有一定的指导意义。

Objective:To investigate the relationship between MSCT findings and pathological risk classification of gastrointestinal stromal tumors(GIST).Methods:MSCT findings of 48 patients with GIST confirmed by surgery,pathology and immunohistochemistry were retrospectively analyzed.The relationship between GIST’s maximum diameter,location,mode of growth,shape,density,degree of enhancement,Ki-67 increment index and pathological risk grade were analyzed.Results:In the 48 patients,18 cases located in stomach,23 cases in intestines,7 cases outside of the gastrointestinal.In 48 cases there were 9 cases of very low or low degree of risk,7 cases of moderate in risk degree,32 cases of high degree.For the three different grade of GISTs,there were statistical significances in the maximum diameter,mode of growth,density,shape,metastasis and Ki-67 increment index(all P<0.05),however,there were no were statistical significances in the location and enhancement degree(P >0.05).Conclusions:The MSCT findings for GIST have certain specificity.It has important value in the diagnosis and evaluating the risk level of tumor,which is helpful for clinical preoperative treatment,and determination of the prognosis.