糖皮质激素性骨质疏松的防治进展

Progress in the prevention and treatment of glucocorticoid induced osteoporosis

糖皮质激素性骨质疏松作为一种继发性骨质疏松,发病率仅次于绝经后的骨质疏松症和老年性的骨质疏松症,是最常见的医源性疾病。糖皮质激素性骨质疏松症状隐匿,早期不易被发现,后期可能出现骨折、骨坏死等一系列并发症,如果得不到有效干预治疗,将会给患者带来极大的健康危险。本文对糖皮质激素性骨质疏松的流行病学及预防与治疗做一综述,旨在加强临床上对于糖皮质激素性骨质疏松防治工作的重视,并为进一步规范治疗提供参考。

As a secondary osteoporosis,the morbidity of the glucocorticoid osteoporosis is next only to postmenopausal osteoporosis and senile osteoporosis.It is the most common iatrogenic disease.The symptoms of glucocorticoid are concealed.It's not easy to be discovered early.In the later period,there may be a series of complications such as fracture and osteonecrosis.If effective intervention is not available,it will bring infinite health risks to patients.This article reviews the epidemiology,prevention and treatment of glucocorticoid induced osteoporosis,aiming at reinforcing the emphasis on the prevention and treatment of glucocorticoid osteoporosis in clinical practice,and providing reference for further standardizing the treatment.