飞秒激光小切口角膜基质透镜取出术术后角膜组织重建与增强术

Corneal remodeling and enhancement after small incision lenticule extraction

飞秒激光小切口角膜基质透镜取出术(SMILE)是一种相对较新的角膜屈光手术方式,近几年来迅猛发展。尽管角膜屈光手术成功率很高,但仍可能因欠矫、过矫、屈光回退等原因而需行增强术,其中角膜上皮和基质重建是屈光回退的主要原因。本文将围绕SMILE术后角膜上皮和基质重建特点、SMILE术后增强术的危险因素、SMILE术后增强术的补矫策略与临床疗效,以及增强术后的组织愈合特点与角膜生物力学差异等临床问题展开综述。

Small incision lenticule extraction(SMILE)is a new option for corneal refractive surgery,which has developed quickly in recent years.Although modern corneal refractive surgery has reached a high success rate,enhancement may be required after refractive surgery.Reasons for enhancement include initial overcorrection or undercor rection and refractive regression,corneal epithelium and stromal remodeling are two main factors contributing to refractive regression.The corneal remodeling process and the risk factors of enhancement after SMILE,and the potential enhancement strategies and their effects,and wound healing process and corneal biomechanics after enhancement are important issues in clinic.This article reviewed relevant literatures and focused on the above issues.