儿科急性上呼吸道感染门诊患儿抗菌药物使用情况分析

Analysis of the use of antibiotics in outpatients with acute upper respiratory tract infections in pediatrics department

目的探讨儿科急性上呼吸道感染门诊患儿的抗菌药物应用合理性。方法选取我院儿科就诊且实验室检查结果记录完整的急性上呼吸道感染门诊患儿900例作为研究对象,分析所有患儿的抗菌药物使用情况及抗菌药物应用的合理性。结果 900例患儿的抗菌药物使用率为82.00%,常用抗菌药物的DDDs由高到低依次为阿奇霉素、头孢他啶、头孢克洛、阿莫西林和头孢唑林。单一用药617例,占83.60%;二联用药112例,占15.18%;三联用药9例,占1.22%。口服用药者375例,占50.81%;静脉注射者363例,占49.19%。排名前5位的抗菌素药物利用指数(DUI)为0.85～1.18,平均DUI为(1.02±0.06)。结论我院儿科门诊抗菌素使用基本合理,应加强对儿科临床抗菌药物应用的管控措施,促进抗菌药物的规范化使用。

Objective To explore the rationality of antibiotic use in outpatients with acute upper respiratory tract infection pediatrics department.Methods A total of 900 outpatients with acute upper respiratory tract infection of pediatrics department in our hospital and had complete records of laboratory examination results were selected as objects of study.The use of antimicrobial drugs of children and the use rationality of antimicrobial drugs were analyzed.Results Of 900 cases of children,the rate of antibiotics use was 82.00%.DDDs of commonly used antimicrobial drugs were azithromycin,ceftazidime,cefaclor,amoxicillin and cefazolin from high to low.There were 617 cases(83.60%)used single drug,112 cases(15.18%)used double drugs and 9 cases(1.22%)used triple drugs.The 375 cases(50.81%)administered the drug orally and 363 cases(49.19%)administered the drug by intravenous injection.The drug utilization index(DUI)of top five antibiotic drugs ranged from 0.85 to 1.18,with an average DUI of(1.02±0.06).Conclusion The use of antibiotics in outpatients of pediatrics department in our hospital is basically reasonable.The control measures of clinical use of antibiotics in pediatrics department should be strengthen,to promote the standardized use of antibiotics.