耐甲氧西林金黄色葡萄球菌的分型及治疗药物研究进展

Classification and therapeutic agents of methicillin-resistant Staphylococcus aureus

抗生素的出现和使用,在减轻患者病痛方面起到一定的积极效果,然临床的滥用,使细菌的耐药发生率逐渐增加。耐甲氧西林金黄色葡萄球菌是细菌耐药的典型致病菌,具有毒性大、类型多、难治疗的临床特性。耐甲氧西林金黄色葡萄球菌除对甲氧西林耐药外,同时对β-内酰胺类、氨基糖苷类、大环内酯类等多种药物耐药,在一定程度上增加了临床治疗的难度,目前已成为医院和社区获得性感染的重要病原菌,其分型和治疗药物分析亦是临床研究的热点。

The emergence and use of antibiotics have played a positive role in alleviating the patients’pain.However,the abuse of antibiotics in clinical practice has gradually increased the incidence of bacterial resistance.Methicillin-resistant Staphylococcus aureus is a typical drug-resistant bacteria.It is clinically characterized by high toxicity,multiple types,and difficult to treat.In addition to methicillin resistance,methicillin-resistant Staphylococcus aureus is resistant to a variety of drugs,such as beta-lactams,aminoglycosides,macrolides,and so on.To a certain extent,it has increased the difficulty of clinical treatment,and has currently become an important pathogen of hospital and community-acquired infections;and its classification and treatment drugs have become the hot spot of clinical research.