心脏MR T2~* mapping技术定量评价2型糖尿病患者左心室心肌改变

Cardiac MR T2~* mapping in quantitative evaluation of left ventricle myocardium in patients with type 2 diabetes mellitus

目的探讨心脏MR T2*mapping技术定量评价2型糖尿病(T2DM)患者心肌改变的临床价值。方法对54例T2DM患者(T2DM组)及43名健康志愿者(正常对照组)采用T2*mapping技术行心脏MR检查。测量并比较2组间左心室各节段心肌及各支冠状动脉供血区心肌T2*值的差异。结果 T2DM组左心室第6、15、16节段T2*值低于正常对照组(P均<0.05),2组间其余各节段心肌T2*值差异均无统计学意义(P均>0.05)。T2DM组冠状动脉左回旋支(LCX)供血区心肌T2*值低于正常对照组(P=0.035),2组间左前降支(LAD)及右冠状动脉(RCA)供血区心肌T2*值差异均无统计学意义(P均>0.05)。结论 T2*mapping技术可用于定量评价T2DM患者左心室心肌改变,有助于早期发现糖尿病心肌病。

Objective To explore the clinical value of cardiac magnetic resonance(CMR)T2*mapping in quantitative evaluation of left ventricle myocardium changes in patients with type 2 diabetes mellitus(T2DM).Methods A total of 54 patients with T2DM(T2DM group)and 43 healthy volunteers(control group)underwent CMR scanning.T2*values of different left myocardial and coronary artery blood supply areas were measured and compared between the two groups.Results T2*values of the 6th,15th and 16th left myocardial segments in T2DM group were lower than those in control group(all P<0.05).There was no statistic difference of T2*values of the other left myocardial segments between the two groups(all P >0.05).T2*values of myocardium in left circumflex artery(LCX)supply area in T2DM group were lower than those in control group(P=0.035),while no statistic difference of left anterior descending coronary artery(LAD)nor right coronary artery(RCA)supply areas T2*values was found between the two groups(all P >0.05).Conclusion T2*mapping technique can be used to quantitatively evaluate myocardial changes of left ventricle in patients with T2DM,which are helpful to early detection of diabetic cardiomyopathy.