银杏内酯注射液辅助治疗缺血性脑卒中患者细胞、血脂因子及生活能力改善效果观察

Ginkgolide injection in improvement of cell and lipid factors as well as life ability in patients with ischemic stroke

目的 探讨给予缺血性脑卒中患者银杏内酯注射液治疗的临床价值。方法 选取2017年6月至2018年6月在本院治疗的90例缺血性脑卒中患者,分为西医组(n=45)、银杏内酯组(n=45),分别给予常规西药、西药+银杏内酯注射液治疗,观察患者细胞因子、血脂指标水平变化情况等。结果治疗后,与西药组相比,银杏内酯组患者IL-6、MMP-9、TNF-α水平及TC、TG、LDL-C水平均显著降低(均P<0.05),银杏内酯组患者MMSE、MoCA、ALD评分显著高于西药组(均P<0.05)。结论 给予缺血性脑卒中患者银杏内酯注射液辅助治疗,可有效改善血脂指标、细胞因子水平,减轻神经功能损伤。

Objective To evaluate the clinical value of ginkgolide injection in the treatment of ischemic stroke.Methods Ninety patients with ischemic stroke treated at our hospital from June,2017 to June,2018 were divided into a western medicine group(n=45)and a ginkgolide group(n=45).The western medicine group were routinely treated with western medicine,and the ginkgolide group with western medicine and ginkgolide injection.The changes of cytokines and blood lipid levels were observed.Results After the treatment,the levels of IL-6,MMP-9,TNF-alpha,TC,TG,and LDL-C were significantly lower and the scores of MMSE,MoCA,and ALD were significantly higher in the ginkgolides group than in western medicine group(all P<0.05).Conclusions Ginkgolide injection for patients with ischemic stroke can effectively improve the blood lipid and cytokine indicators and alleviate nerve function damage.