不同浓度舒芬太尼用于妇科术后静脉镇痛效果的比较

Comparison of Different Concentrations of Sufentanil for Intravenous Analgesia after Gynecological Surgery

目的:探讨妇科患者应用不同浓度舒芬太尼进行麻醉后镇痛效果。方法:选取2016年3月-2018年3月本院收治的妇科手术患者90例。按照随机数字表法将其分为A、B、C组,各30例,分别给予1.5、2.0、2.5μg/kg舒芬太尼进行镇痛。比较三组麻醉诱导前(T1)、术后30 min(T2)、手术结束前1 min(T3)、导管拔除后5 min(T4)、术后1 h(T5)的心率、平均动脉压,比较三组麻醉恢复情况、疼痛程度评分及不良反应发生情况。结果:三组T4、T5的心率、平均动脉压比较差异均有统计学意义(P<0.05),其中B、C组均优于A组(P<0.05);三组麻醉恢复情况、疼痛程度评分比较,差异均有统计学意义(P<0.05),其中A、B组自主呼吸恢复时间、苏醒时间、拔管时间均短于C组(P<0.05),B、C组疼痛程度评分均低于A组(P<0.05);三组嗜睡、头晕发生率比较差异均有统计学意义(P<0.05)。结论:妇科患者应用不同浓度舒芬太尼进行麻醉后镇痛效果显著,2.0μg/kg的剂量具有一定的优越性,既可改善术后疼痛程度,又可提高麻醉恢复情况,值得临床应用。

Objective:To investigate the effect of different concentrations of Sufentanil for intravenous analgesia after gynecological surgery.Method:A total of 90 patients with gynecological surgery admitted to our hospital from March 2016 to March 2018 were selected.According to the method of random number table,they were divided into A,B and C groups,30 cases in each group,and Sufentanil was given 1.5,2.0 and 2.5μg/kg respectively for analgesia.The heart rate and mean arterial pressure before induction of anesthesia(T1),30 minutes after operation(T2),1 minute before end of operation(T3),5 minutes after catheter removal(T4)and 1 hour after operation(T5)were compared in three groups,the recovery of anesthesia,pain score and adverse reactions between three groups were compared.Result:The heart rate and mean arterial pressure of T4 and T5 in three groups were compared,the differences were statistically significant(P<0.05),B and C group were better than those of A group(P<0.05).The recovery of anesthesia and the degree of pain were compared in three groups,the differences were statistically significant(P<0.05),and the recovery time of spontaneous breathing,recovery time and extubation time in A and B group were shorter than those of C group(P<0.05),the pain scores in B and C group were lower than those of A group(P<0.05).The incidence of somnolence and dizziness in three groups were compared,the differences were statistically significant(P<0.05).Conclusion:Different concentrations of Sufentanil in gynecological patients have significant analgesic effect after anesthesia.The dosage of 2.0μg/kg has certain advantages.It can not only improve the degree of pain after operation,but also improve the recovery of anesthesia.It is worthy of clinical application.