舒芬太尼联合地佐辛用于上腹部手术后自控镇痛的临床研究

The clinical study of the combined application of sufentanil and dizoxin in the control of pain after upper abdominal surgery

目的:探讨上腹部手术后自控镇痛中联合运用地佐辛和舒芬太尼的临床效果。方法:选择我院2015年10月-2016年10月期间收治的行上腹部手术患者110例为研究对象,根据随机抽样法将其分为两组,其中对照组行昂丹司琼+舒芬太尼自控镇痛,而观察组则运用舒芬太尼+地佐辛自控镇痛,对比分析两组镇痛效果。结果:与对照组比较,观察组术后2 h、6 h、12 h、24 h以及48 h的VAS评分均较低,组间对比差异明显(P <0.05);相比较对照组而言,观察组的不良反应发生率低,组间比较有明显差异(P <0.05);同时,两组的自控镇痛次数对比有差异(P <0.05)。结论:临床上给予上腹部手术后患者舒芬太尼+地佐辛联合镇痛可以获得较好的镇痛效果。

Objective:To explore the clinical effect of the combined application of sufentanil and dizoxin in the control of pain after upper abdominal surgery.Method:110 cases of upper abdominal surgery patients admitted to our hospital from October 2015 to October 2016 were selected as study subjects.They were divided into two groups according to the random sampling method.The control group received ondansetron+sufentanil automatic analgesia,while the observation group used sufentanil+dizoxin automatic analgesia.Result:VAS scores 2 h,6 h,12 h,24 h and 48 h after surgery were lower,and the differences between the groups were significant(P<0.05).Compared with the control group,the incidence of adverse reactions in the observation group was lower and there were significant differences between the groups(P<0.05).At the same time,there was a difference in the number of times of self-control analgesia between the two groups(P<0.05).Conclusion:Clinically,the combined sufentanil and dizoxin could obtain a better analgesic effect after upper abdominal surgery.