散结通络汤治疗湿热瘀阻型结节性红斑临床观察

Clinical observation of Sanjie Tongluo decoction on erythema nodosum of damp-heat and blood-stasis obstruction

目的:观察散结通络汤治疗结节性红斑的临床疗效。方法;60例患者按随机数字表法分为治疗组和对照组各30例。对照组口服白芍总苷胶囊治疗,治疗组口服散结通络汤治疗;疗程1个月。观察临床疗效及治疗前后血沉、C反应蛋白等主要指标。结果:治疗组总有效率为83.33%;对照组为63.33%,治疗组临床疗效优于对照组(P﹤0.05);治疗组和对照组均能降低患者的血沉、C反应蛋白数值(P﹤0.01),治疗后两组C反应蛋白差异非常显著,治疗组优于对照组(P﹤0.01)。结论:散结通络汤治疗结节性红斑疗效明确,在临床疗效、降低C反应蛋白方面优于口服白芍总苷胶囊治疗。

Objective:To observe the clinical effect of Sanjie Tongluo decoction on erythema nodosum(EN).Methods:60 cases of patients with EN were randomly divided into treatment group and control group,30 cases in each group.The control group was treated with oral total glucosides of paeony capsules,while the treatment group was treated with oral Sanjie Tongluo decoction,and the course of treatment was 1 month.The clinical effect and the main indexes of erythrocyte sedimentation rate and C-reactive protein etc.before and after treatment were evaluated.Results:The total effective rate of clinical treatment was 83.33%in treatment group and 63.33%in control group.The clinical effect of treatment group was better than that of control group(P<0.05).Treatment group and control group both could reduce erythrocyte sedimentation rate and C-reactive protein of patients(P<0.01).After treatment,the difference of C-reactive protein between two groups was very significant,and the treatment group was better than control group(P<0.01).Conclusion:The clinical effect of Sanjie Tongluo decoction on erythema nodosum is definite and better than that of oral total glucosides of paeony capsules in clinical effect and reducion of C-reactive protein.