摘要
慢性心力衰竭(CHF)的发病率和病死率均很高,故探寻与其诊断和预后相关的新心肌生物标志物有着重要意义。可溶性生长刺激表达基因2蛋白(sST2)和半乳糖凝集素-3 (Gal-3)作为新兴的辅助心肌生物标志物而备受重视。二者在心室重构过程中发挥着重要作用。CHF患者血清sST2和Gal-3水平升高。本文就sST2联合Gal-3对CHF的诊断及预后价值作一综述。
Morbidity and mortality of chronic heart failure(CHF)are high.Therefore,it's of great significance to explore new myocardial biomarkers related to its diagnosis and prognosis.As emerging complementary myocardial biomarkers,soluble growth stimulation expressed gene 2 protein(sST2)and Galectin-3(Gal-3)receive lots of attention.Both of them play important role during ventricular remodeling.Serum levels of sST2 and Gal-3 rise in CHF patients.The present article made a review on diagnostic and prognostic value of sST2 combined Gal-3 for CHF.
作者
张丹丹
张瑶
ZHANG Dan-dan;ZHANG Yao(Department of Cardiology,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)
出处
《心血管康复医学杂志》
CAS
2019年第1期109-111,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
心力衰竭
诊断
预后
Heart failure
Diagnosis
Prognosis
