深静脉血栓后综合征研究进展

Treatment and progress of post thrombotic syndrome

深静脉血栓后综合征(PTS)是下肢深静脉血栓形成(DVT)的远期后遗症,即便DVT早期给予规范化抗凝治疗,仍然有较高的PTS发病率。深静脉瓣膜受损反流、静脉压增高、静脉血回流受阻被认为是PTS的主要形成机制。传统PTS治疗方法包括抗凝、弹力袜、运动疗法及药物治疗等。采用经皮血管成形术(PTA)和专用静脉支架治疗PTS已经取得了良好的疗效,临床被广泛接受。本文对PTS的病理生理、临床诊断及治疗进行综述,以便进一步指导临床治疗。

Post thrombosis syndrome(PTS)is a long-term sequelae of deep venous thrombosis(DVT).Even if DVT is given standardized anticoagulant therapy at an early stage,there is still a high incidence of PTS.Deep venous valve injury reflux,increased venous pressure,and blocked venous blood flow are considered to be the main formation mechanisms of PTS.Traditional PTS treatments include anticoagulant therapy,elastic compression socks,exercise therapy,and drug therapy.Percutaneous angioplasty and dedicated venous stents to treat PTS have achieved good results and have been widely accepted clinically.This article reviews the clinical diagnosis and treatment of PTS in order to further guide the clinical treatment.