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自杀风险生物标志物的研究现状

Research situation of suicide risk biomarkers
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摘要 自杀是一种复杂的社会现象,受心理、生物、环境等多种因素的相互作用。到目前为止,临床医师评估患者自杀风险的最佳方法是筛查患者的自杀未遂史。然而,近期研究发现神经生物学可能对自杀风险具有预测价值。现对有关自杀风险生物标志物的国内外研究进行归纳性介绍。 Suicide is a complex social phenomenon,which is affected by psychological,biological and environmental factors.To date,the best method for clinicians to assess a patient s suicide risk is to screen for a patient s history of attempted suicide.However,recent studies have found that neurobiology may have predictive value for suicide risk.This paper summarizes the research on suicide risk biomarkers in China and abroad.
作者 娄月 胡建 Lou Yue;Hu Jian(Mental Health Center,the First Affiliated Hospital of Harbin Medical University,Harbin 150000,China)
出处 《神经疾病与精神卫生》 2019年第1期88-91,共4页 Journal of Neuroscience and Mental Health
关键词 自杀 预测 标志物 综述 Suicide Predict Biomarkers Review
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  • 1Pandey GN, Ren X, Rizavi HS, et al. Brain-derived neurotrophic factor and tyrosine kinase B receptor signalling in post-mortem brain of teenage suicide victims [ J ]. Int J Neuropsychopharmacol, 2008,11 : 1047-1061.
  • 2Bocchio-Chiavetto L, Bagnardi V, Zanardini R, et al. Serum and plasma BDNF levels in major depression : a replication study and meta-analyses[ J]. World J Biol Psychiatry,2010,11:763-773.
  • 3Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications : meta-analysis and implications[J]. Biol Psychiatry,2008,64:527-532.
  • 4Shimizu E, Hashimoto K, Okamura N, et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants[ J]. Biol Psychiatry ,2003, 54:70-75.
  • 5Gonul AS, Akdeniz F, Taneli F, et al. Effect of treatment on serum brain-derived nenrotrophic factor levels in depressed patients [ J ]. Eur Arch Psychiatry Clin Neurosci ,2005,255:381-386.
  • 6Lee.BH, Kim H, park SH, et al. Decreased plasma BDNF level in depressive Patients[J]. J Affect Disord,2007,101:239-244.
  • 7Duman RS. Role of neurotrophic factors in the etiology and treat- ment of mood disorders [ J ]. Neuromolecular Med,2004,5 : 11-25.
  • 8Karege F, Schwald M, Cisse M. Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets [ J ].Neurosci Lett,2002,328:261-264.
  • 9Siuciak JA, Lewis DR, Wiegand SJ, et al. Antidepressant-like effect of brain-derived neurotrophic factor (BDNF) [J]. Pharmacol Bio- chem Behav, 1997,56 : 131-137.
  • 10Kim YK,Lee HP,Won SD,et al. Low plasma BDNF is associated with suicidal behavior in depression [ J ]. Prog Neuropsychophar- macol Biol Psychiatry,2007,31:578-579.

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