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线粒体动力学紊乱在精神分裂症中作用的研究进展

Research progress of the role of mitochondrial dynamics disorders in schizophrenia
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摘要 线粒体是细胞的能量加工厂,线粒体代谢与线粒体动力学密切相关。研究表明线粒体动力学障碍在神经发育中有重要的影响,与精神分裂症紧密相关。本文就动力学异常与神经发育及精神分裂症的相关性作一综述。 M itochondria are energy processing plants for cells.Mitochondrial metabolism is closely related to mitochondrial dynamics which plays the key role in nervous system development.Recent studies show that m itochondrial dynamics disorders lias been thought to contribute to the pathophysiology of schizophrenia.This article discusses the influence of mitochondrial dynamics on nervous system development,and review recent work suggesting the relation between aberrant mitochondrial dynamics and schizophrenia.
作者 汪崇泽 费慧 孟美玲 谢帆 Wang Chongze;Fei Hui;Meng Meiling;Xie Fan(Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China;Shanghai Jiading District Mental Health Center,Shanghai 201823,China)
出处 《神经疾病与精神卫生》 2019年第1期91-95,共5页 Journal of Neuroscience and Mental Health
关键词 精神分裂症 线粒体动力学 综述 Schizophrenia Mitochondrial dynamics Review
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