摘要
疫苗作为预防疾病的重要措施,为人类预防各种传染病起到了巨大的作用,可产生有益的"免疫反应",也可以产生不利甚至造成损害的不良反应,部分不良反应表现在皮肤。疫苗相关的皮肤不良反应临床表现多样机制复杂,本文主要阐述疫苗相关的皮肤不良反应的现状,有助于理解和认识疫苗不良反应的发生机制和不同的临床表现形式。
Vaccine is an important measure to prevent diseases,and plays a great role in preventing various infectious diseases.Vaccine can not only produce a beneficial"immune response",but also induce adverse reactions or even adverse damage,some of which manifest as skin lesions.Clinical manifestations of vaccine-associated cutaneous adverse reactions are various,and their pathogenesis is complex.This review mainly elaborates the current status of vaccine-associated cutaneous adverse reactions,which may help to understand the pathogenesis and different clinical manifestations of vaccine adverse reactions.
作者
向睿宇
冯素英
Xiang Ruiyu;Feng Suying(Department of Dermatology,Hospital for Skin Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs,Nanjing 210042,China)
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2019年第2期128-131,共4页
Chinese Journal of Dermatology
基金
中国医学科学院医学与健康科技创新工程项目(CIFMS-2017-I2M-1-017)
中央级公益性科研院所基本科研业务费(2016ZX320014)
北京协和医学院协和青年基金(3332016107).
关键词
疫苗
药物毒性
皮肤表现
疫苗不良反应
Vaccines
Drug toxicity
Skin manifestations
Vaccine adverse reactions