光暴露紊乱对炎症性肠病的影响

Influence of Light Exposure on Inflammatory Bowel Disease

光暴露是十分重要的环境因素。光暴露紊乱可能导致生物节律或睡眠的紊乱,使生物钟基因表达、褪黑素分泌、肠道免疫功能和菌群等发生改变。光暴露紊乱可能对炎症性肠病(IBD)患者病情存在一定的影响。本文就光暴露紊乱对IBD的影响作一综述。

Light exposure is a very important environmental factor.Increased light exposure may lead to disturbed circadian rhythm or sleep,resulting in dysregulation of the circadian clock gene,secretion of melatonin,intestinal immunity,and bacterial flora,which in turn affect the condition of IBD patients.This article reviewed the effect of light exposure on IBD.