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白癜风发病机制的研究 被引量：9

Pathogenic mechanism research of vitiligo
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摘要 白癜风是一种常见的皮肤色素脱失性疾病,其发病机制迄今尚未明确。该病发病机制复杂,涉及遗传、免疫、氧化应激、神经体液、黑素细胞凋亡和丢失、紫外线损伤机制等。 Vitiligo is an common depigmentation disease of skin,and the pathogenic mechanisms has not been completely expounded.The pathogenesisis is complex,involving genetic,immune,oxidative stress,neurohumor,melanocyte apoptosis and loss,ultraviolet damage and so on.
作者 但晓 吴一菲 DAN Xiao;WU Yi-fei(Clinical Medical College,Dali University,Dali 671000,Yunnan;Department of Dermatology,the First People’s Hospital of Yunnan Province,Kunming 650100,Yunnan)
机构地区 大理大学临床医学院 云南省第一人民医院
出处 《皮肤病与性病》 2019年第1期23-26,共4页 Dermatology and Venereology
关键词 白癜风 发病机制 研究 Vitiligo Pathogenesis
分类号 R751.02 [医药卫生—皮肤病学与性病学] R758.41 [医药卫生—皮肤病学与性病学]
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  • 1McEligot, A.J., Largent, J., Ziogas, A., Peel, D., and Anton-Cuiver, H. (2006). Dietary fat, fiber, vegetable, and micronutrients are associated with overall survival in postmenopausal women diagnosed with breast cancer. Nutr. Cancer 55: 132-140.
  • 2Miller, J.W., Nadeau, M.R., Smith, J., Smith, D., and Selhub, J. (1994). Folate-deficiency-induced homocysteinaemia in rats: Disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism. Binchem. J. 298 (Pt 2): 415-419.
  • 3Niculescu, M.D. (2002). Diet, methyl donors and DNA methylation:Interactions between dietary folate, methionine and choline. J. Nutr. 132: 2333S-2335S.
  • 4Nijhout, H.F., Reed, M.C., Anderson, D.F., Mattingly, J.C., James, S.J., and Ulrich, C.M. (2006a). Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 1:81-87.
  • 5Nijhout, H.F., Reed, M., Lam, S., Shane, B., Gregory, J., and Ulrich, C. (2006b). In silico experimentation with a model of hepatic mito- chondrial folate metabolism. Theor. Biol. Med. Model. 3: 40.
  • 6Nijhout, H.F., Reed, M.C., Budu, P., and Ulrich, C.M. (2004). A mathematical model of the folate cycle: New insights into folate homeostasis. J. Biol. Chem. 279: 55008-55016.
  • 7Paz, M.F., Avila, S., Fraga, M.F., Pollan, M., Capella, G, Peinado, M.A., Sanchez-Cespedes, M., Herman, J.G., and Esteiler, M. (2002). Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. Cancer Res. 62:4519-4524.
  • 8Pullarkat, S.T., Stoehlmacher, J., Ghaderi, V., Xiong, Y.P., Ingles, S.A., Sherrod, A., Warren, R., Tsao-Wei, D., Groshen, S., and Lenz, H.J. (2001). Thymidylate synthase gene polymorphism determines re- sponse and toxicity of 5-FU chemotherapy. Pharmacogenomics J. 1: 65-70.
  • 9Rampersaud, G.C., Kauwell,G.P., Hutson, A.D., Cerda, J.J., and Bailey, L.B. (2000). Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am. J. Clin. Nutr. 72: 998-1003.
  • 10Reed, M.C., Nijhout, H.F., Neuhouser, M.L., Gregory, J.F., Ill, Shane, B., James, S.J., Boynton, A., and Ulrich, C.M. (2006). A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J. Nutr. 136: 2653-2661.

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皮肤病与性病
2019年 第1期

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