中西医结合治疗老年缺血性心肌病心衰46例临床观察

Clinical Observation on the Treatment of Ischemic Cardiomyopathy and Heart Failure with Combination of Traditional Chinese and Western Medicine

目的:观察参麦注射液联合硝酸甘油治疗老年缺血性心肌病心衰的效果及其对患者心功能的影响。方法:将92例老年缺血性心肌病心衰患者,随机分为对照组(46例,硝酸甘油治疗)和观察组(46例,参麦注射液联合硝酸甘油治疗)。观察两组疗效和不良反应情况,对比两组脑钠肽(BNP)水平及心功能指标。结果:观察组的治疗总有效率为93. 48%,显著高于对照组的76. 09%(P <0. 05)。治疗后,观察组血清BNP水平及左室短轴缩短率(LVFS)、左心室射血分数(LVEF)、每搏输出量(SV)等心功能指标改善情况均优于对照组的19. 57%(P <0. 05)。观察组的不良反应发生率为4. 35%,显著低于对照组(P <0. 05)。结论:中西医结合治疗老年缺血性心肌病心衰的疗效明显,可有效改善患者的心功能,缓解心衰症状,且不良反应发生率低。

Objective To observe the effect of shenmai infection combined nitroglycerin in cardiac function of elderly patients with ischemic cardiomyopathy and heart failure.Methods 92 elderly patients with ischemic cardiomyopathy and heart failure were divided into control group(n=46,treated with nitroglycerin)and observation group(n=46,treated with shenmai infection combined nitroglycerin).The clinical efficacy and untoward effect were observed in two groups.The level of brain natriuretic peptide(BNP)and cardiac function were compared in two groups.Results The total effective rate of observation group was higher than control group(P<0.05).The changes of serum BNP and left ventricular shortening fraction(LVFS),left ventricular ejection fraction(LVEF),stroke volume(SV)in observation group were better than those in control group(P<0.05).The rate of untoward effect in observation group was 4.35%,which was lower than control group(P<0.05).Conclusion Traditional Chinese combine with western medicine has good efficacy in treatment of elderly patients with ischemic cardiomyopathy and heart failure.It can effectively improve the heart function,alleviate symptoms of heart failure,also has low incidence of adverse reactions.