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外用粒细胞/巨噬细胞集落刺激因子凝胶联合硼酸治疗重度失禁性皮炎的效果观察 被引量:3

Effect observation of granulocyte/macrophage colony stimulating factor hydro-gel combined with boronic acid on severe incontinence dermatitis
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摘要 目的:探讨外用粒细胞/巨噬细胞集落刺激因子联合硼酸治疗重症患者重度失禁性皮炎((Incontinence-associated dermatitis,IAD)创面的效果。方法:将100例重度IAD的重症患者随机分为干预组和对照组各50例,干预组患者在创面常规清洗后给予4%硼酸湿敷10 min后外涂粒细胞/巨噬细胞集落刺激因子凝胶,每天4次;对照组患者在创面常规清洗后给予涂抹造口护肤粉后喷3M液体敷料,每天4次。观察两组患者的治疗效果、创面愈合时间、治疗过程所需护理时数。结果:干预组患者的治疗效果、创面愈合时间、治疗过程所需护理时数与对照组比较差异有统计学意义(P<0.05)。结论:外用粒细胞/巨噬细胞集落刺激因凝胶子联合硼酸能促进重症患者重度IAD创面愈合,缩短愈合时间,减轻护理工作量。
作者 马洁葵
出处 《天津护理》 2019年第1期103-104,共2页 Tianjin Journal of Nursing
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  • 1李福伦,李斌,王振宜,徐蓉,范斌,徐文彬,金伟,肖秀丽,王一飞.SD大鼠糖尿病创面与正常创面中TGF-β1、TGF-β3的表达差异[J].中国美容医学,2007,16(1):35-37. 被引量:10
  • 2Mann A, Breuhahn K, Schirmacher P, et al. Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing: stimulation of keratinocyte proliferation, granulation tissue formation, and vascularization. J Invest Dermatol,2001 , 117 (6) : 1382-1390.
  • 3Jaschke E, Zabernigg A, Gattringer C. Recombinant human granulocyte-macrophage colony-stimulating factor applied locally in low doses enhances healing and prevents recurrence of chronic venous ulcers. Int J Dermatol, 1999, 38(5) :380-386.
  • 4Masucci G. New clinical application of granulocyte-macrophage colony-stimulating factor. Med Oncol, 1996,13 (3) : 149-154.
  • 5Masucci G, Broman P, Kelly C, et al. Therapeutic efficacy by recombinant human granulocyte/monocyte-colony stimulating factor on mucositis occurring in patients with oral and oropharynx tumors treated with curative radiotherapy: a muhicenter open randomized phase Ⅲ study. Med Oneol, 2005,22 (3) :247-256.
  • 6Groves RW, Schmidt-Lucke JA. Recombinant human GM-CSF in the treatment of poorly healing wounds. Adv Skin Wound Care, 2000 ,13(3) :107-112.
  • 7Fang Y, Gong SJ,Xu YH,et al. Impaired cutaneous wound healing in granulocyte/macrophage colony-stimulating factor knockout mice. Br J Dermatol, 2007,157 ( 3 ) :458-465.
  • 8Mann A, Niekisch K, Schirmacher P, et al. Granulocyte-macrophage colony-stimulating factor is essential for normal wound healing. J Investig Dermatol Symp Proc, 2006 , 11 ( 1 ) :87-92.
  • 9于勇,蒋伟,常东,姜玲敏,杨小强,冷金昌,刘小乡.临床感染病原菌的变迁及其与抗菌药物应用的关系[J].感染.炎症.修复,2007,8(3):131-136. 被引量:10
  • 10Gray M, Bliss Dz, Ermer - Sulten J, et al. Incontinence - associated dermatitis: a consensus.J Wound Ostonw Continence Nurs, 2007,34 (1):45-54.

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