摘要
利用有机高价碘中的亚碘酰苯(PhIO)对苯乙酮进行α-乙酰氧化,并分别就溶剂、水、亚碘酰苯(PhIO)和催化剂三氟化硼乙醚的用量,以及反应温度对反应的影响进行了讨论.在得出的较优反应条件下,最高分离收率可达86.5%.该反应条件温和,操作简便,选择性好,为合成α-乙酰氧基苯乙酮提供了一种简便有效的新方法.
Iodosobenzene(PhIO)was used to acetoxylate acetophenones.The effects of solvent,water,relative dosage of PhIO and catalyst,and temperature on the reaction were discussed.Under the optimum reaction conditions,the highest separation yield was as high as 86.5%.In conclusion,the reaction conditions are mild,the operation is simple and the selectivity is good.It provides a simple and effective new method for the synthesis of alpha-acetoxyacetophenones.
作者
段益琴
张财
周永福
傅相锴
穆瑞珠
DUAN Yi-qin;ZHANG Cai;ZHOU Yong-fu;FU Xiang-kai;MU Rui-zhu(School of Chemistry and Chemical Engineering,Southwest University/Chongqing Key Laboratory of Applied Chemistry,Chongqing 400715,China;Faculty of Chemistry and Pharmaceutical Engineering,Chongqing Industry Polytechnic College,Chongqing 401120,China;Department of Building and Environmental Safety,Chongqing Vocational Institute of Safety and Technology,Chongqing 404020,China)
出处
《西南大学学报（自然科学版）》
CAS
CSCD
北大核心
2019年第1期84-88,共5页
Journal of Southwest University(Natural Science Edition)
基金
重庆市教委科学技术研究计划项目(KJ1603009
KJ1603006)
重庆工业职业技术学院校级重点科研项目(GZY201603-ZK)
关键词
高价碘
亚碘酰苯
乙酰氧化
苯乙酮
hypervalent iodine
iodosobenzene
acetoxylation
acetophenone
