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原发性肝癌精准肝切除术临床效果观察及患者血清miR-199a/b-3p水平变化 被引量:8

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摘要 目的观察原发性肝癌精准肝切除术的临床效果及患者血清miR-199a/b-3p水平变化。方法将108例肝癌患者按随机数字表法分为两组各54例,观察组行精准肝切除术治疗,对照组行传统肝切除术治疗。比较两组肝门阻断率、术中出血量、手术时间、术后住院时间、总住院费用,检测血清肝功能(ALT、TBIL、AST、ALB)、miR-199a/b-3p,记录术后并发症及术后1年复发情况。结果与对照组比较,观察组肝门阻断率低、术中出血量少、手术时间长、术后住院时间短、总住院费少(P均<0. 05);两组术前肝功能及血清miR-199a/b-3p比较差异无统计学意义,术后观察组ALT、TBIL、AST低于对照组而ALB、miR-199a/b-3p高于对照组(P均<0. 05);观察组术后并发症发生率、术后1年复发率均低于对照组(P均<0. 05)。结论肝癌患者行精准肝切除术治疗,可有效降低肝门阻断率、减少术中出血量、减轻肝功能损害,提高血清miR-199a/b-3p水平,降低术后并发症发生率及肝癌复发率,减轻患者的经济负担。
出处 《山东医药》 CAS 2019年第5期68-70,共3页 Shandong Medical Journal
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