基因联合间充质干细胞移植治疗老年性ED的研究进展

Research progress in thetreatment of gene therapy combined mesenchymal stem cells for aged erectile dysfunction

勃起功能障碍(erectile dysfunction,ED)的发病率与年龄相关,随着老龄人口的增加,老年ED患者也不断增多。目前仍未找到最适当的治疗方法治愈或阻止ED的发生发展。虽然老年性ED的基因治疗是一个新兴的热点,但是联合间充质干细胞(Mesenchymal stem cells,MSCs)移植更是对运用基因治疗ED的升华,本文将对各种基因联合间充质干细胞移植治疗老年性ED进行综述。

The incidence of erectile dysfunction(ED)is associated with age.With the increase of elderly population,there is an increasing number of aged ED patients.The most appropriate treatment to cure or prevent the development of ED is still unclear.Although gene therapy is a new focus in the aged ED,the combination with Mesenchymal stem cells transplantation is an improved therapy for ED.This paper summarizes the treatment of gene therapy combined mesenchymal stem cells for aged ED.