生长抑制剂配合急诊手术治疗急性胆囊炎的疗效分析

Efficacy Analysis of Growth Inhibitor Combined with Emergency Surgery in the Treatment of Acute Cholecystitis

目的探讨生长抑制剂配合急诊手术治疗急性胆囊炎的疗效分析。方法收集我院2014年9月-2016年9月收治的150例急性胆囊炎患者,随机分为观察组和对照组各75例,对照组予以急诊手术治疗;观察组在对照组的基础上加用生长抑制剂治疗,比较两组疗效。结果观察组因术中炎性组织粘连较重而转开腹手术者1例(1.33%),对照组因局部组织炎性渗出和水肿程度较重转开腹手术者12例(16.0%);观察组术后炎性指标水平均低于对照组(P<0.05);观察组术后发热、恶心呕吐、腹痛等临床症状恢复时间均短于对照组,差异有统计学意义(P<0.05);观察组术后不良反应总发生率(17.3%)明显低于对照组(34.7%),差异具有统计学意义(P<0.05)。结论生长抑制剂能减少胆汁的分泌,减轻炎性反应,减轻病灶周围组织渗出、水肿、粘连,能提高急诊手术的成功率,减少手术并发症的发生,促进患者尽快恢复。

Objective To investigate the efficacy of growth inhibitor combined with emergency surgery in the treatment of acute cholecystitis.Methods 150 patients with acute cholecystitis treated in our hospital from September 2014 to September 2016 were randomly divided into observation group(75 cases)and control group(75 cases).Both groups were given emergency surgical treatment;besides,the observation group was given additional growth inhibitor,the efficacies of the two groups were compared.Results In the observation group,1 case(1.33%)was converted to open surgery due to severe inflammatory tissue adhesion during operation,12 cases(16.0%)were converted to open surgery due to severe inflammatory exudation and edema in the control group.The inflammatory index level of the observation group was lower than that of the control group(P<0.05).The recovery time of clinical symptoms such as fever,nausea vomiting and abdominal pain in the observation group was shorter than that in the control group(P<0.05).The total incidence of postoperative adverse reactions in the observation group(17.3%)was significantly lower than that in the control group(34.7%)(P<0.05).Conclusion Growth inhibitor can reduce bile secretion,inflammatory reaction,exudation,edema and adhesion around lesions,improve the success rate of emergency surgery,reduce the incidence of surgical complications and promote the recovery of patients as soon as possible.