CT定量测量与CR在COPD急性加重期患者肺功能的不同价值对比

Comparison of CT Quantitative Measurements and Different Values of CR in Lung Function in Patients with Acute Exacerbation of COPD

目的探讨CT定量测量与CR在评估COPD急性加重期肺功能的不同价值。方法选择2015年1月至2016年12月在我院就诊的COPD急性加重期167例患者,所有患者均行肺功能检查、多层螺旋CT(MSCT)定量分析和计算机X摄影(CR)检查。评估MSCT定量指标和CR测量与肺功能相关性。结果 Vex、Vin与RV、TLC、RV/TLC呈正相关(P<0.05),与FEV1、FVC、FEV1/FVC呈负相关(P<0.05);Vex/Vin与RV、RV/TLC呈正相关,与FEV1、FVC、FEV1/FVC呈负相关(P<0.05),MLDin与其相反(P<0.05);MLDex、MLDex-MLDin与RV、TLC、RV/TLC呈负相关,与FEV1、FVC、FEV1/FVC呈正相关(P<0.05)。肺高与RV、TLC、RV/TLC呈正相关),与FEV1、FEV1/FVC呈负相关(P<0.05);左肋膈角、右膈顶与前肋关系与RV、RV/TLC呈正相关,与FEV1、FVC、FEV1/FVC呈负相关(P<0.05);右下肺动脉横径、右肋膈角与FEV1、FEV1/FVC呈负相关(P<0.05);右膈顶与后肋关系和FEV1、FEV1/FVC呈负相关(P<0.05);膈弓高度与TLC呈正相关(P<0.05)。结论 MSCT可定量检查肺容积和密度,且与肺功能改变具有显著相关性,因此MSCT在COPD急性加重期早期诊断优于CR。

Objective To explore the different value of CT quantitative measurement and CR in evaluating lung function during acute exacerbation of COPD.Methods 167 patients with acute exacerbation of COPD in our hospital were selected,all of them underwent pulmonary function examination,quantitative detection of multislice spiral CT(MSCT)and computer X-ray(CR)examination.To assess the correlation between MSCT quantitative indicators and CR measurements and lung function.Results There are different degrees of correlation between the above indexes.Conclusion MSCT can quantitatively examine lung volume and density and is significantly correlated with changes in lung function.Therefore,early diagnosis of MSCT in the acute exacerbation of COPD is superior to CR.