MR弥散加权成像表观弥散系数在前列腺疾病诊断中的应用

Application of Apparent Di ffusion Coefficient of MR Diffusion-weighted Imaging on the Diagnosis of Prostate Disease

目的分析磁共振(Magnetic Resonance,MR)弥散加权成像(diffusion weighted imaging,DWI)表观弥散系数(apparent diffusion coefficient,ADC)在前列腺疾病诊断中的应用价值。方法选取我院收治的72例前列腺疾病患者,并取同期36名健康体检者纳入对照组,均行MR常规扫描以及MR-DWI检查,选出感兴趣区(regionsofinterest,ROI),详细记录DWI信号强度与ADC值,对所得数据进行统计学分析。结果 b=50s/mm2、800s/mm2时,前列腺癌组DWI信号强度均明显高于前列腺增生组与对照组(P<0.05),但前列腺增生组与对照组DWI信号强度比较无明显差异(P>0.05);b=800s/mm2时,前列腺癌组ADC值明显小于前列腺增生组与对照组(P<0.05),前列腺增生组与对照组ADC值比较无显著差异(P>0.05)。结论 MR-DWI ADC值测定可为前列腺疾病诊断提供有效依据,对鉴别前列腺癌与前列腺增生具有重要指导意义。

Objective To analyze the application value of apparent diffusion coefficient(ADC)of magnetic resonance(MR)diffusion weighted imaging(DWI)in the diagnosis of prostate disease.Methods 72 patients with prostate disease admitted to the hospital were enrolled.36 healthy subjects in the same period were enrolled in the control group.All of them were given routine MR scan and MR-DWI examination.The regions of interest(ROI)were chosen.The signal intensity of DWI and ADC value were detailedly recorded.Statistical analysis was performed on the obtained data.Results When b equaled to 50s/mm2 and 800s/mm2,the signal intensity of DWI in prostate cancer group was significantly higher than that in prostatic hyperplasia group and control group(P<0.05).There was no significant difference in signal intensity of DWI between prostatic hyperplasia group and control group(P >0.05).When b equaled to 800s/mm2,the ADC value of prostate cancer group was significantly lower than that of prostatic hyperplasia group and control group(P<0.05).There was no significant difference in ADC value between prostatic hyperplasia group and control group(P >0.05).Conclusion The measurement of MR-DWI ADC value can provide an effective basis for the diagnosis of prostate diseases,which has important guiding significance for the differential diagnosis of prostate cancer and prostatic hyperplasia.