血清HCG、AFP水平联合MRI在前置胎盘植入及其分类诊断中的应用

Application of Levels of Serum HCG and AFP Combined with MRI in Implantation and Classification Diagnosis of Placenta Previa

目的探讨血清人绒毛膜促性腺激素(HCG)、甲胎蛋白(AFP)水平联合磁共振成像(MRI)在前置胎盘植入及其分类诊断中的应用。方法选择我院收治的65例前置胎盘植入患者为前置胎盘植入组,另选择同期收治的60例单纯前置胎盘患者为单纯前置胎盘组,50例无前置胎盘无植入产妇为对照组,三组产妇产前均进行血清HCG、AFP与MRI检查,比较不同检查方法对前置胎盘植入及其分类诊断结果。结果前置胎盘植入组血清HCG、AFP水平均显著高于单纯前置胎盘组和对照组(P<0.05)。穿透型患者血清HCG、AFP水平均显著高于粘连型和植入型(P<0.05),植入型患者血清HCG水平显著高于粘连型(P<0.05)。HCG+AFP+MRI对粘连型胎盘植入检出率为96.55%,对植入型胎盘植入检出率为95.65%,对穿透型胎盘植入检出率为100%,均高于单纯血清HCG、AFP和MRI检测。结论血清HCG、AFP联合MRI可明确前置胎盘植入及胎盘植入类型,临床应用价值较高。

Objective To investigate the application of levels of serum human chorionic gonadotropin(HCG)and alpha fetoprotein(AFP)combined with magnetic resonance imaging(MRI)in implantation and classification diagnosis of placenta previa.Methods65 patients with placenta previa implantation in the hospital were enrolled in the placenta previa implantation group.The other 60 patients with single placenta previa in the same period were enrolled in the single placenta previa group.50 parturients without placenta previa or implantation were enrolled in the control group.The serum HCG,AFP and MRI examination were performed on parturients in the three groups.The results of placenta previa implantation and classification diagnosis with different examination methods were compared.Results The levels of serum HCG and AFP in the placenta previa implantation group were significantly higher than those in the single placenta previa group and the control group(P<0.05).The levels of serum HCG and AFP in the penetrating patients were significantly higher than those in the adhesion type and implanted type patients(P<0.05).The serum HCG level of the implanted patients was significantly higher than that of the adhesion type patients(P<0.05).The implantation detection rates of adhesion placenta,implanted placenta and penetrating placenta with HCG with AFP and MRI were 96.55%,95.65%and 100%,respectively,all higher than those with either of the three.Conclusion Serum HCG,AFP combined with MRI can identify the placenta previa implantation and type of placenta implantation.