腹膜转移癌患者采用MRI联合弥散加权成像诊断的曲线下面积、灵敏度和特异度研究

Area Under the Curve(AUC), Sensitivity and Specificity of MRI Combined with Diffusion-weighted Imaging in Diagnosis of Peritoneal Metastasis

目的探讨MRI联合弥散加权成像对腹膜转移癌患者的临床诊断价值。方法选择2014年2月至2015年3月在我院进行治疗的疑似腹膜转移癌患者56例,所有入选患者均行MRI常规扫描联合弥散加权成像扫描。结果在入选的56例疑似腹膜转移癌患者中经病理检查及随访,有43例确诊为腹膜转移癌。MRI及MRI联合DWI的ROC曲线下面积分别为0.681和0.817,差异有统计学意义(P<0.05)。MRI对腹膜转移癌的灵敏度、特异性、阳性及阴性预测值分别为85.7%,53.8%,85.7%和53.8%;MRI联合DWI对腹膜转移癌的灵敏度、特异性、阳性及阴性预测值分别为92.9%,71.4%,90.7%和76.9%。结论 MRI联合弥散加权成像诊断腹膜转移癌相对于单独利用MRI具有更高的临床价值,可在临床推广应用。

Objective To investigate the clinical diagnostic value of MRI combined with diffusion weighted imaging in patients with peritoneal metastasis.Methods A total of 56cases of patients with peritoneal metastasis from February 2014 to March 2015 in our hospital were selected.All patients were diagnosed with MRI and MRI combined with diffusion weighted imaging.Results All the 56 suspected cases of peritoneal metastasis were examined by pathological examination and follow-up,43 cases were confirmed diagnosed as peritoneal metastasis.The area under the DWI curve of MRI,MRI and ROC was 0.681and 0.817,respectively,the difference was significant(P<0.05).The sensitivity,specificity,positive and negative predictive value of MRI for diagnosis of peritoneal metastasis were85.7%,53.8%,85.7%and 53.8%,respectively.The sensitivity,specificity,positive and negative predictive value of MRI combined with DWI for peritoneal metastasis were92.9%,76.9%,90.7%and 71.4%respectively.Conclusion MRI combined with diffusion weighted imaging has a higher clinical value than that of MRI alone in the diagnosis of peritoneal metastasis,which can be used in clinical application.