遗传相关性卒中的研究进展

Research Progress of Hereditary Stroke

遗传因素与卒中发生密切相关,明确基因与卒中的相关关系,有利于卒中的预防、诊断和治疗。近年来随着技术手段的发展,越来越多的卒中相关基因位点被发现,而既往已知的基因也对诊疗有新的指导意义。本文主要介绍遗传相关性卒中,包括镰状细胞病、Fabry病、遗传性胶原蛋白病、高同型半胱氨酸血症以及近期基因位点多态性的相关研究。

Genetic factors are highly associated with stroke.Clarifying the relationship between gene and stroke will help us to make strategies for the prevention,diagnosis and treatment of stroke.With the development of new technologies,more and more genetic loci were discovered.This article mainly reviewed hereditary stroke including sickle cell disease,Fabry disease,hereditary collagen disease,hyperhomocysteinemia,and recent research advance in gene polymorphism.