胎儿颈项透明层增厚与胎儿水囊状淋巴管瘤

The increased nuchal translucency and cystic hygroma fetuses

胎儿颈项透明层(NT)增厚与水囊状淋巴管瘤(CH)是早孕期能被发现的两个重要的胎儿高危标记物,与胎儿的染色体异常、各种器官结构异常、遗传综合征风险增加有关,NT、CH的正确解读与后续的诊疗关系密切。本文从胚胎发育的角度阐述NT、CH的形成原理,分析二者的关系,并对其超声异常的诊断、预后分析、诊疗策略进行比较总结。

An increased nuchal translucency()and cystic hygroma(CH)are two important markers for abnormal fetus in first trimester pregnancy,which are relevant with karyotype abnormality,fetal structural anomalies,and genetic syndrome of fetus.The correct interpretation of NT and CH is closely related to subsequent diagnosis and treatment.In this article,the principle of NT and CH based is reviewed in detail based on early embryonic development,and the relationship between NT and CH is analyzed.Additionally,the difference of prenatal diagnosis,abnormal outcomes,and treatment are summarized and compared between NT and CH.