乙肝病毒感染合并肺结核的临床治疗分析

Analysis of clinical treatment for hepatitis B virus infection combined with tuberculosis

目的探讨乙肝病毒感染合并肺结核的临床治疗方法及临床效果。方法选取80例乙肝病毒感染合并肺结核患者作为研究对象,随机分为观察组(n=40)和对照组(n=40),对照组患者采取抗结核治疗+保肝治疗,观察组在对照组治疗基础上加用拉米夫定进行治疗。对比两组患者的治疗总有效率以及干预前后肝功能指标。结果观察组患者治疗总有效率为92.5%,对照组患者治疗总有效率为75%,两组对比差异具有统计学意义(P <0.05)。干预前两组患者肝功能指标对比差异无统计学意义(P> 0.05),干预后观察组患者肝功能代表性指标明显优于对照组,对比差异具有统计学意义(P <0.05)。结论对于乙肝病毒感染合并肺结核患者给予抗结核治疗+保肝治疗+拉米夫定进行联合治疗,能够有效提高患者的治疗效果以及改善患者的肝功能。

Objective To investigate the clinical treatment and clinical effects of hepatitis B virus infection combined with pulmonary tuberculosis.Methods Eighty patients with hepatitis B virus infection and pulmonary tuberculosis were selected as subjects.They were randomly divided into observation group(n=40)and control group(n=40).The control group patients received anti-tuberculosis treatment+liver protection treatment.The observation group was treated with lamivudine for treatment on basis therapy of the control group..The total effective rate of treatment between the two groups and the representative indicators of liver function before and after intervention were compared.Results The total effective rate was 92.5%in the observation group and 75%in the control group.The difference between the two groups was statistically significant(P<0.05).There was no significant difference in the representative indexes of liver function between the two groups before intervention(P>0.05).The representative indexes of liver function in the observation group were significantly better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion Combined treatment with anti-tuberculosis treatment+liver protection+lamivudine for patients with hepatitis B virus infection and pulmonary tuberculosis can effectively improve the treatment effect of patients and improve the liver function of patients.