阿莫西林克拉维酸钾治疗小儿尿路感染的临床效果

Clinical effect of Amoxicillin and Clavulanate Potassium in the treatment of urinary tract infection in children

目的探讨阿莫西林克拉维酸钾治疗小儿尿路感染的临床效果。方法回顾性分析2015年9月～2017年9月我院收治的118例尿路感染患儿的临床资料,按照治疗方法的不同将其分为对照组和观察组,每组各59例。其中采用头孢曲松钠治疗的患儿作为对照组,采用阿莫西林克拉维酸钾治疗的患儿作为观察组。比较两组患儿的临床治疗效果、退热时间、尿菌转阴时间、细菌清除率及不良反应发生情况。结果观察组患儿的治疗总有效率为96.61%,高于对照组的84.44%,差异有统计学意义(P<0.05)。观察组患儿的退热时间、尿菌转阴时间均短于对照组,差异有统计学意义(P<0.05)。观察组患儿的细菌清除率为95.59%,高于对照组的81.54%,差异有统计学意义(P<0.05)。观察组患儿的不良反应总发生率为5.08%,与对照组的8.47%比较,差异无统计学意义(P>0.05)。结论阿莫西林克拉维酸钾治疗尿路感染具有良好的效果,能明显缩短患儿的治愈时间,细菌清除率更高,不良反应少,值得临床应用及推广。

Objective To explore the clinical effect of Amoxicillin and Clavulanate Potassium in the treatment of urinary tract infection in children.Methods The clinical data of 118 children with urinary tract infection admitted to our hospital from September 2015 to September 2017 were retrospectively analyzed.According to the different treatment methods,they were divided into the control group and the observation group,with 59 cases in each group.Children treated with Ceftriaxone Sodium were selected as the control group,and children treated with Amoxicillin Clavulanate Potassium were selected as the observation group.The clinical treatment effect,antipyretic time,urinary bacteria turning into negative time,bacterial clearance rate and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.61%,which was higher than that in the control group(84.44%),and the difference was statistically significant(P<0.05).The antipyretic time and urinary bacteria turning into negative time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The bacterial clearance rate of the observation group was 95.59%,which was higher than that of the control group(81.54%),and the difference was statistically significant(P<0.05).The total incidence rate of adverse reactions in the observation group was 5.08%,compared with 8.47%in the control group,and the difference was not statistically significant(P >0.05).Conclusion Amoxicillin and Clavulanate Potassium has a good effect in the treatment of urinary tract infection,and it can significantly shorten the healing time of children,has higher bacterial clearance rate and fewer adverse reactions,which is worthy of clinical application and promotion.