氨氯地平治疗劳力性心绞痛的效果及安全性

Effect and safety of amlodipine in the treatment of exertional angina pectoris

目的探讨氨氯地平治疗劳力性心绞痛的效果及安全性。方法将100例劳力性心绞痛患者按照治疗方法的不同分为对照组(n=50,常规治疗)和观察组(n=50,常规治疗+氨氯地平)。比较两组治疗效果。结果治疗后,两组心绞痛发作频率及持续时间均减少,且观察组少于对照组(P<0.05)。观察组的不良反应总发生率、死亡率低于对照组(P<0.05)。结论氨氯地平治疗劳力性心绞痛的效果可靠,安全性较高,值得临床推广应用。

Objective To investigate the effect and safety of amlodipine in the treatment of exertional angina pectoris.Methods A total of 100 patients with exertional angina pectoris were divided into control group(n=50,routine treatment)and observation group(n=50,routine treatment+amlodipine)according to different treatment methods.The therapeutic effects of the two groups were compared.Results After treatment,the frequency and duration of angina pectoris in both groups decreased,and those in the observation group were less than the control group(P<0.05).The total incidence of adverse reactions and mortality in the observation group were lower than those in the control group(P<0.05).Conclusion Amlodipine is effective and safe in the treatment of exertional angina pectoris,which is worthy of clinical application.