C反应蛋白联合血常规检验在儿科疾病诊断中的应用效果分析

Analysis of Application Effect of C Reactive Protein Combined with Blood Routine Test in Diagnosis of Diseases in the Department of Pediatrics

目的研究C反应蛋白与血常规检验在儿科疾病诊断中的应用情况,并探讨其应用价值。方法该次研究共选取2017年6月—2018年6月期间的96例儿童作为研究对象,其中46例为来常熟市第一人民医院儿科就诊的患儿作为研究组,50名来医院体检的健康儿童作为对照组,两组患儿均开展CRP与血常规检查,比较两组的检验结果。结果对照组CRP水平(3.12±0.11)mg/dL与白细胞计数(5.6±1.0)×109/L和中性粒细胞计数(0.35±0.07)×109/L显著低于研究组[(71.24±3.58)mg/dL,(25.4±6.1)×109/L,(1.31±0.12)×109/L],组间差异有统计学意义(t=134.540 9、22.633 8、48.342 8,P=0.000 0、0.000 0、0.000 0);单独应用CRP检验时,诊断的敏感性为72.00%,特异性为58.70%,准确性为65.63%,单独应用血常规检验的敏感性为64.00%,特异性为54.35%,准确性为59.38%,CRP与血常规联合检验的敏感性为96.00%,特异性为91.30%,准确性为93.75%,CRP与血常规联合检验的特异性,敏感性与准确性均高于单独应用CRP检验或是单独应用血常规检验,组间差异有统计学意义。结论 CRP与血常规检查在儿科感染性疾病诊断中的准确性较高,且具有操作便捷,所用时间较短的特点,可以为患儿疾病的治疗提供依据。

Objective To study the application effect of C reactive protein combined with blood routine test in diagnosis of diseases in the department of pediatrics.Methods 96 cases of children from June 2017 to June 2018 were selected as the research objects,including 46 cases of children diagnosed in the first people’s hospital of Changshu,and 50 cases of healthy children for physical examination,and the CRP and blood routine examination were conducted,and the test results were compared between the two groups.Results The CRP level,white blood cell count and neutrophils count in the control group were obviously belower than those in the research group[(3.12±0.11)mg/dL,(5.6±1.0)×10^9/L,(0.35±0.07)×10^9/L vs(71.24±3.58)mg/dL,(25.4±6.1)×10^9/L,(1.31±0.12)×10^9/L],and the differences were obvious,with statistical significance,(t=134.540 9,22.633 8,48.342 8,P=0.000 0,0.000 0,0.000 0),and the single application of CRP test showed that the diagnostic sensitivity,specificity and accuracy were respectively 72.00%,58.70%and 65.63%,and the sensitivity,specificity and accuracy of single application of blood routine test were respectively 64.00%,54.35%and 59.38%,and the sensitivity,specificity and accuracy of CRP and blood routine test were respectively 96.00%,91.30%,93.75%,and the differences were obvious,with statistical significance.Conclusion The accuracy of CRP and blood routine test in the infectious diseases in the department of pediatrics is higher,with simple operation and short use time,and it can provide reference for the treatment of children’s diseases.