TIA对继发性CI的影响因素分析

Analysis of the influence factors of TIA on secondary CI

目的分析TIA(短暂性脑缺血发作)对继发性脑梗死的影响及其相关危险因素。方法选取2017年5月至2018年10月本院收治的短暂性脑缺血发作患者中选取320例,以是否继发脑梗死为依据,分为非脑梗死组与脑梗死组,另外再选取本院同时期收治的无短暂性脑缺血发作脑梗死患者118例为研究对象,将其归为对照组,分析TIA进展至脑梗死的相关危险因素以及TIA对继发性脑梗死的影响。结果多因素结果显示,影响TIA进展为脑梗死的相关因素包括颈动脉硬化斑块、糖尿病史、高血压病史、年龄;脑梗死患者预后分级、神经功能缺损均优于对照组,差异具有统计学意义(P<0.01)。结论颈动脉硬化斑块、糖尿病史、高血压病史、年龄是影响TIA进展到脑梗死的主要危险因素,并且TIA出现之后引发的缺血耐受能够有效保护后继脑梗死的神经功能,将脑梗死患者的神经功能缺损程度降低。

Objective To analyze the effect of TIA on secondary cerebral infarction and its related risk factors. Methods From May 2017 to October 2018, 320 patients with transient ischemic attack were selected and divided into non-cerebral infarction group and cerebral infarction group. In addition, 118 patients with cerebral infarction without transient ischemic attack in the same period were selected as control group. The risk factors related to the progression of TIA to cerebral infarction and the effect of TIA on secondary cerebral infarction were analyzed. Results Multivariate results showed The impact of TIA progress on cerebral infarction related factors including carotid atherosclerotic plaque, diabetes history, hypertension history, age, prognosis classification of cerebral infarction, neural function defect are superior to the control group (P<0.01). Conclusion Carotid atherosclerotic plaque, diabetes history, hypertension history, age are the main risk factors affecting the progression of TIA to cerebral infarction Moreover, the ischemic tolerance induced by TIA can effectively protect the neurological function of subsequent cerebral infarction and reduce the degree of neurological deficit in patients with cerebral infarction.