腹腔镜手术与超声引导下穿刺治疗卵巢子宫内膜异位囊肿对卵巢储备功能及IVF-ET结局的影响

The effects of laparoscopic surgery and ultrasound-guided puncture on ovarian reserve function and IVF-ET outcome in ovarian endometriotic cysts

目的探讨腹腔镜手术与超声引导下穿刺治疗卵巢子宫内膜异位囊肿对卵巢储备功能及IVF-ET结局的影响。方法选取2015年1月至2018年1月于本院行IVF-ET的卵巢子宫内膜异位囊肿患者65例,以治疗方式不同将36例超声引导下穿刺患者作为穿刺组,29例腹腔镜手术患者作为腔镜组,观察比较两组患者的卵巢储备功能及IVF-ET结局。结果穿刺组术后AFC、血清AMH水平高于腔镜组,血清FSH、LH、E2水平均低于腔镜组,差异有统计学意义(P<0.05);穿刺组获卵数高于腔镜组,差异有统计学意义(P<0.05),两组患者在受精率、临床妊娠率及早期流产率差异无统计学意义。结论腹腔镜手术较超声引导下穿刺术对卵巢储备功能造成的影响更大,但两种治疗方法对IVF-ET结局的影响差异无统计学意义。

Objective To investigate the effects of laparoscopic surgery and ultrasound-guided puncture on ovarian reserve function and IVF-ET outcome in ovarian endometriotic cysts. Methods Sixty-five patients with ovarian endometriotic cysts who underwent IVF-ET in our hospital from January 2015 to January 2018 were enrolled. According to the treatment, 36 patients underwent ultrasound-guided puncture as the puncture group and 29 patients underwent laparoscopic surgery as the laparoscopic group. Ovarian reserve function and IVF-ET outcome were compared between the two groups. Results The levels of AFC and serum AMH in the puncture group were higher than those in the laparoscopic group. The levels of serum FSH, LH and E2 were lower than those in the laparoscopic group (P<0.05). The number of eggs in the puncture group was higher than that in the laparoscopic group. There was statistical significance (P<0.05). There was no significant difference in fertilization rate, clinical pregnancy rate and early abortion rate between the two groups. Conclusion Laparoscopic surgery has a greater impact on ovarian reserve than ultrasound-guided puncture, but there was no statistically significant difference in the effect of the two treatments on IVF-ET outcome.