电视胸腔镜手术治疗非小细胞肺癌患者的疗效观察

Effect observation of video-assisted thoracic operation on treatment of patients with non-small cell lung cancer

目的探讨电视胸腔镜手术治疗非小细胞肺癌患者的疗效。方法将130例非小细胞肺癌患者随机分为2组各65例。对照组采用传统开胸手术,观察组采用电视胸腔镜手术。比较2组患者术后第5、10天C反应蛋白(CRP)水平以及手术时间、住院时间、淋巴结清扫数量和心肺术后并发症发生情况。结果观察组患者术后第5、10天的CRP水平、住院时间均显著低于对照组(P <0. 05),手术时间显著长于对照组(P <0. 05)。2组淋巴结清扫数目无显著差异(P> 0. 05)。2组患者手术后肺炎和脓胸等并发症发生率无显著差异(P> 0. 05);观察组心律失常和伤口感染发生率均显著低于对照组(P <0. 05)。结论电视胸腔镜治疗原发性非小细胞肺癌安全有效,其具有创伤小、手术时间短、住院时间短及并发症少等优势。

Objective To explore the effect of video-assisted thoracoscopic surgery on the treatment of patients with non-small cell lung cancer(NSCLC).Methods Totally 130 patients with NSCLC were randomly divided into observation group and control group,with 65 cases in each group.The control group was treated with conventional thoracotomy,while the observation group was treated with video-assisted thoracoscopic surgery.The levels of C reactive protein(CRP)at 5 and 10 days after operation,operation time,hospital stay,number of lymph node dissection and complications after cardiopulmonary surgery were compared between the two groups.Results The CRP level at 5 and 10 days after operation and hospitalization time in the observation group were significantly lower than those in the control group(P<0.05),and the operation time was significantly longer than that in the control group(P<0.05).There was no significant difference in the number of lymph node dissection between the two groups(P>0.05).There was no significant difference in the incidence rate of complications such as pneumonia and empyema between the two groups(P>0.05).The incidence rates of arrhythmia and wound infection in the observation group were significantly lower than those in the control group(P<0.05).Conclusion Video-assisted thoracoscopic surgery is safe and effective in the treatment of patients with primary NSCLC,which has the advantages of less trauma,shorter operation time,shorter hospitalization time and fewer complications.