支气管扩张患者营养风险与疾病严重程度相关性研究

Correlation between nutritional risk and severity of disease in patients with bronchiectasis

目的探讨营养风险评分(NSR2002)对支气管扩张症患者相关临床指标的影响,分析该疾病急性加重次数的相关影响因素。方法将70例支气管扩张症患者依据NSR2002评分表分为A组(NSR≥3分)与B组(NSR<3分),每组35例。比较2组患者一般资料,分析影响患者住院风险的独立危险因素。结果 2组一般资料比较无显著差异(P>0.05),除第1秒用力呼气容积占预计值百分比(FEV1%)、二氧化碳分压[p(CO2)]无显著差异外(P>0.05),2组其他指标均有显著差异(P<0.05)。影响疾病急性加重次数的独立危险因素为病程、抗生素使用时间、呼吸困难量表(m MRC)、C反应蛋白(CRP)、NSR评分(P<0.05)。结论营养风险较高的患者疾病年急性加重次数较多,需要更长时间的抗生素进行治疗。支气管扩张症患者病程、抗生素使用时间、m MRC、CRP、NSR评分可作为预测该疾病急性加重的影响因素。

Objective To explore the influence of nutritional risk score(NSR2002)on related clinical indicators of patients with bronchiectasis and analyze the related factors of the number of acute exacerbations of the disease.Methods A total of 70 patients with bronchiectasis were divided into group A(NSR≥3 points)and group B(NSR<3 point)according to NSR2002 scale,with 35 cases in each group.The general materials of two groups were compared,and the independent risk factors for hospitalization risk were analyzed.Results There were no significant differences in general materials between the two groups(P>0.05).Except for the percentage of forced expiratory volume in the first second(FEV 1%)and the partial pressure of carbon dioxide[p(CO 2)](P>0.05),there were significant differences in other indicators between the two groups(P<0.05).The independent risk factors affecting the number of acute exacerbations were course of disease,time of antibiotic use,dyspnea scale(mMRC),C-reactive protein(CRP)and NSR score(P<0.05).Conclusion Patients with higher nutritional risk have more acute exacerbations per year and need longer treatment course of antibiotics.The course of disease,antibiotic use time,mMRC,CRP and NSR scores can be used as factors to predict the acute exacerbation of the disease in patients with bronchiectasis.