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甲泼尼龙冲击治疗儿童睡眠中癫痫性电持续状态的效果观察

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摘要 目的:观察甲泼尼龙冲击治疗儿童睡眠中癫痫性电持续状态(ESES)的临床效果。方法:选取89例ESES患儿为研究对象,采用简单随机化法将其分为观察组45例和对照组44例。对照组行常规治疗,观察组在对照组基础上行甲泼尼龙冲击治疗。比较两组治疗效果、不良反应发生率及治疗前后智力发育情况。结果:观察组治疗总有效率为93.3%(42/45),明显高于对照组的77.3%(34/44),差异有统计学意义(P<0.05);观察组不良反应发生率为13.33%(6/45),略高于对照组的2.27%(1/44),差异无统计学意义(P>0.05);治疗后,两组韦氏智力量表评分均明显升高,且观察组评分明显高于对照组,差异均有统计学意义(P<0.05)。结论:在临床常规治疗基础上,甲泼尼龙冲击治疗可有效改善ESES患儿的临床症状,提高患儿智力,且安全性好。
作者 赵红艳
出处 《中国民康医学》 2019年第2期71-72,共2页 Medical Journal of Chinese People’s Health
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