摘要
临床药师全程参与1例Ⅳ度骨髓抑制患者的救治过程,结合紫杉醇相关不良反应基因多态性检测,分析骨髓抑制与药物之间的关系,并对治疗方案提出修改建议,保障了患者的用药安全和疗效。
Clinical pharmacists have involved in the treatment of the patient with IV degree of marrow depression,analyzing the relationship between marrow depression and drugs,combined with the polymorphisms of the related genes that impact the paclitaxel toxicity,proposing the suggestion of adjusting drug therapy to ensure the safe and effective clinical treatment for the patient.
作者
王海叶
衣翠华
方英立
WANG Hai-ye;YI Cui-hua;FANG Ying-li(Qilu Hospital of Shandong University,Jinan Shandong 250012,China;Handan Central Hospital,Handan Hebei 056001,China)
出处
《药品评价》
CAS
2019年第4期7-8,60,共3页
Drug Evaluation
关键词
临床药师
紫杉醇脂质体
骨髓抑制
基因多态性
Clinical Pharmacist
Paclitaxel Liposome
Marrow Depression
Genetic Polymorphism