摘要
因具有聚集诱导发光特性、螺旋桨结构的四苯乙烯及其衍生物,在有机光电材料、荧光传感和生物成像等领域表现出优异的荧光性能。本实验以二苯甲酮为原料,利用McMurry偶联反应合成四苯乙烯。采用萃取、干燥和柱层析等手段对产物进行分离和纯化,通过熔点测定、核磁共振氢谱、核磁共振碳谱和质谱对其结构进行表征后,使用苦味酸作为模型化合物,利用荧光光谱测定其对爆炸物的荧光检测极限。本实验寓科研热点于实验教学中,不仅提高了学生的实验操作技能,而且有助于学生了解具有聚集诱导发光性能的四苯乙烯及其衍生物的研究现状和应用前景,激发了学生的科研兴趣和创新意识。
Tetraphenylethylene and its derivatives with propeller structure have excellent fluorescence properties,which can be applied to the fields of organic photo-electric materials,fluorescence sensing and biological imaging due to the aggregation-induced fluorescence property.In this experiment,tetraphenylethylene was synthesized by McMurry coupling reaction using benzophenone as starting materials.The target compound was separated and purified by extraction,drying and column chromatography,and its structure was characterized by the melting point measurement,1H NMR,13C NMR,and MS.The fluorescence detection limit for explosives was determined by fluorescence spectra using picric acid as a model compound.This experiment with the research focuses can improve the students’experimental skills,help students to understand the current status and applications of tetraphenylethylene and its derivatives with aggregation-induced fluorescence property,and stimulate students’interest in scientific research and innovation consciousness.
作者
何田
顾峥烨
尹守春
HE Tian;GU Zhengye;YIN Shouchun(Provincial Chemical Experimental Teaching Demonstrating Center,College of Material,Chemistry and Chemical Engineering,Hangzhou Normal University,Hangzhou 310036,P.R.China)
出处
《大学化学》
CAS
2019年第1期48-53,共6页
University Chemistry
基金
浙江省"十二五"省级实验教学示范中心重点建设项目(浙教办函(2015)173号)
浙江省MOOC/SPOC课程培育项目
杭州师范大学高等教育课堂教学改革研究项目
关键词
四苯乙烯
聚集诱导发光
综合实验
荧光
爆炸物检测
Tetraphenylethylene
Aggregation-induced emission
Comprehensive experiment
Fluorescence
Explosive detection