盐酸纳布啡术前应用于腹腔镜卵巢囊肿剔除术患者的镇痛观察

Nalbuphine for the effect of preemptive analgesia of laparoscopic ovarian cyst surgery on postoperative analgesia

目的观察盐酸纳布啡超前镇痛对腹腔镜卵巢囊肿剔除术患者围术期的镇痛效果。方法将60例ASAⅠ～Ⅱ级择期腹腔镜卵巢囊肿剔除手术患者随机分为A、B组,每组30例。A组诱导前30min静脉注射盐酸纳布啡0.3mg/kg;B组诱导前静脉注射与A组相同容积的生理盐水。分别于于术后1h、4h、8h、12h、24、48h记录患者对疼痛的视觉模拟评分(VAS),于术后48h记录患者满意程度评分(BCS)和患者按压PCA泵的总次数和有效按压次数。结果术后1h、4h、8h、12h、48hVAS评分A组均<B组(P<0.05),BCS评分A组均>B组(P<0.05),而2组48h VAS评分比较差异无统计学意义;术后48h PCA的总按压次数和有效按压次数A组明显<B组(P<0.05)。结论盐酸纳布啡用于腹腔镜卵巢囊肿剔除术超前镇痛,能有效减少术后患者对PCA的按压次数,提高镇痛质量。

Objective To observe the effects of nalbuphine hydrochloride preemptive analgesia in laparoscopic ovarian cyst postoperative analgesia.Methods 60 cases of ASA I^II elective laparoscopic ovarian cyst removal surgery patients were randomly divided into A,B group,each group of 30 cases.A group of preoperative 30min intravenous injection of nalbuphine hydrochloride 0.3mg/kg;saline intravenous injection A group with the same volume of B group before operation.The visual analogue scale(VAS)of 1h,4h,8h,12h,24and 48h were recorded respectively,and the total score(BCS),the total pressing times and effective pressing times of PCA 48h were recorded after the end of analgesia.Results After 1h,4h,8h,12h,24and 48h VAS scores of A group were lower than those in group B(P<0.05),the BCS score in A group were higher than that of group B(P<0.05),while the two group 48h VAS score had no significant difference;after the total number of PCA 48h press and press times of A group was significantly lower than that of group B(P<0.05).Conclusion Nalbuphine hydrochloride for laparoscopic ovarian cyst resection of preemptive analgesia can reduce postoperative patients of small pressing times of PCA,improve the quality of analgesia.