不稳定型心绞痛中医证型与冠状动脉病变积分的相关性研究

Correlation between TCM Syndromes of Unstable Angina and Gensini Score of Coronary Stenosis

目的探讨不稳定型心绞痛中医证型与冠状动脉病变积分的相关性。方法将150例不稳定型心绞痛病人辨证分型,进行冠状动脉造影并采用Gensini评分评定冠状动脉病变程度。结果不稳定型心绞痛病人中,女性偏于心气虚弱型、心肾阴虚型、心肾阳虚型等虚证;而男性偏于心血瘀阻型、痰浊内阻型、心气虚弱型等;随着年龄的增加,男性、女性病人多表现为心气虚弱型、心肾阴虚型、心肾阳虚型等虚证。心肾阳虚型Gensini积分均高于其他5型。结论不稳定型心绞痛病人中医证型与性别、年龄存在一定的相关性,心肾阳虚型冠脉病变最为严重,心肾阳虚是不稳定型心绞痛重症独立的危险因素。

Objective To explore correlation between traditional Chinese medicine (TCM) syndromes of unstable angina and Gensini score of coronary stenosis. Methods Syndrome differentiation and coronary angiography were carried out in 150 patients with unstable angina pectoris. Results The blood stagnation syndrome,phlegm and turbid stagnatio syndrome,heart qi deficiency syndrome occurred mainly in male patients,while heart qi deficiency syndrome,heart and kidney yin deficiency syndrome,heart and kidney yang deficiency syndrome occurred mainly in female patients. With the increase of age,male and female patients are often characterized by heart qi deficiency syndrome,heart and kidney yin deficiency syndrome,heart and kidney yang deficiency syndrome and other deficiency syndromes. Gensini score in patients with heart and kidney yang deficiency syndrome were significantly increased compared to the others groups. Conclusion There is a certain correlation between TCM syndrome type and gender and age in patients with unstable angina. The heart and kidney yang deficiency syndrome is the risk factor of severe coronary artery stenosis.