虹膜角膜内皮综合征的研究进展

Progress of iridocorneal endothelial syndrome

虹膜角膜内皮综合征(iridocorneal endothelial syndrome, ICES)是一种罕见的眼部疾病,是一组以角膜内皮、前房角和虹膜的结构及增生异常为特征的疾病。常见的临床特征包括角膜水肿、继发性青光眼、虹膜萎缩、瞳孔异常等。常发生于年轻女性,多单眼发病。其发病机制尚不明确,症状多样,且致盲率高。该疾病诊断困难,且尚无理想治疗方法。本文旨在回顾有关ICES的特点、诊断及治疗等方面的文献,以期对疾病的诊治提供帮助。

·Iridocorneal endothelial syndrome(ICES)is a rare ocular disease characterized by abnormal structure and proliferation of the corneal endothelium,the anterior chamber angle,and the iris.Common clinical features include corneal edema,secondary glaucoma and iris atrophy.ICES often occurs in young women,and most of them are monocular.Its pathogenesis is still unclear,the symptoms are various,and the blindness rate is high.The disease is difficult to diagnose,and there is no ideal treatment.The purpose of this article is to review the literature on the characteristics,diagnosis and treatment of ICES in order to help the diagnosis and treatment of the disease.