呼吸机相关事件及其预防的研究进展

Research progress in ventilator-associated events and prevention

对于长期行机械通气的危重患者,医院内肺炎是影响患者临床预后的关键因素。既往,呼吸机相关肺炎(VAP)一直作为呼吸机相关感染并发症的重要监控手段,但因其标准主观性大、灵敏度和特异度低,具有较大的争议。因此,美国疾病控制与预防中心在2013年提出了呼吸机相关事件(VAE)的定义,该监测定义采用客观的量化标准,能够较好地预测患者的临床结局。本文总结了近年来VAE的研究进展,为更好地防控VAE提供一些新的思路。

Healthcare-associated pneumonia(HAP)is a key factor affecting the clinical prognosis of critically ill patients undergoing long-term mechanical ventilation.In the past,ventilator-associated pneumonia(VAP)was an important mean of monitoring complications of ventilator-associated infection,but it is highly controversial because of its high subjectivity,low specificity and poor sensitivity.Therefore,the definition of ventilator-associated event(VAE)was proposed by Centers for Disease Control and Prevention of USA in 2013,the monitoring definition adopts objective and quantitative criteria,which can better predict the clinical outcomes of patients.This paper summarizes the research progress of VAE in recent years,and provides some new ideas for better prevention and control of VAE.