美托洛尔干预Brugada综合征合并高血压1例

A case report of metoprolol intervention in Brugada syndrome with hypertension

1例44岁男性患者,因无明显诱因出现"心慌、胸骨后疼痛2 h"入院,既往"反复晕厥"病史3年,无器质性心脏病病史。入院后查体、查心肌酶及冠状动脉造影均未见异常。心电图示:窦性心律,心率73次·min^(-1),V_1、V_2导联呈鞍型抬高0.2～0.3 mV,诊断为Brugada综合征。给予美托洛尔(12.5 mg,q 12 h)及厄贝沙坦(150 mg,qd)口服后症状缓解。出院后继续服药,随访38个月,患者未出现明显不适症状。

One 44-year-old male patient was admitted because of palpitation and retrosternal pain for 2 hours. The patient had a 3-year history of recurrent syncope, while had no history of organic heart disease. There was no abnormality in physical examination, myocardial enzymes and coronary angiography after admission. The electrocardiogram showed sinus rhythm, heart rate 73 times per minute, saddle elevation of 0.2 – 0.3 mV in lead V1 and V2. The patient was diagnosed as Brugada syndrome. The symptoms were relieved after using oral administration of metoprolol (12.5 mg, q 12 h) and irbesartan (150 mg, qd). The patient continued taking those medicines after discharging from hospital. The patient was followed up for 38 months, and there was no cardiac event occurred.