柴胡疏肝散治疗高血压合并焦虑状态临床观察

Clinical Observation on Chaihu Shugan Powder in the Treatment of Hypertension with Anxiety

目的分析柴胡疏肝散加减对高血压合并焦虑状态的治疗效果。方法择取50例高血压合并焦虑状态患者,收治时间从2015年12月—2017年12月,将上述患者分为2组,各25例。给予对照组患者口服苯磺酸氨氯地平片及氟哌噻吨美利曲辛片,研究组患者在上述基础上增加口服柴胡疏肝散加减方,观察2组患者的临床治疗效果、血压治疗后的变化情况、HAMA总分治疗前后的变化情况。结果研究组患者当中,20例患者为显效,占80%,4例患者为有效,占16%,无效患者为1例,占4%;对照组患者当中,15例患者为显效,占60%,2例患者为有效,占8%,无效患者为8例,占32%。研究组患者的收缩压是(136.8±12.8)mm Hg,舒张压是(80.6±4.9)mm Hg;对照组患者的收缩压是(143.9±10.3)mm Hg,舒张压是(90.4±5.3)mm Hg;治疗前研究组患者的HAMA总分是(23.3±2.8)分,治疗后的HAMA总分是(10.6±0.9)分,治疗前对照组患者的HAMA总分是(23.9±2.3)分,治疗后的HAMA总分是(19.4±2.3)分。结论柴胡疏肝散加减对高血压合并焦虑状态患者的临床治疗效果较好,能显著稳定患者的血压,同时缓解患者的焦虑状态,值得临床上的广泛推广。

Objective To analyze the therapeutic effect of Chaihu Shugan powder on hypertension and anxiety.Methods Fifty patients with hypertension and anxiety were divided into two groups,with 25 patients in each group from December 2015 to December 2017.Patients in the control group were given amlodipine besylate tablets and droperidol-methotrexate tablets orally.Patients in the study group were given Chaihu Shugan powder on the basis of the above.The clinical effects,blood pressure changes and HAMA scores of the two groups were observed before and after treatment.Results Among the study group,20 cases were markedly effective,accounting for 80%,4 cases were effective,accounting for 16%,1 case was ineffective,accounting for 4%.In the control group,15 cases were markedly effective,accounting for 60%,2 cases were effective,accounting for 8%,8 cases were ineffective,accounting for 32%.In the study group,the systolic and diastolic blood pressure was(136.8±12.8)mmHg and(80.6±4.9)mm Hg.The systolic and diastolic blood pressures of the control group were(143.9±10.3)mmHg and(90.4±5.3)mmHg respectively.The total score of HAMA was(23.3±2.8)in study group before treatment,(10.6±0.9)in HAMA after treatment,(23.9±2.3)in control group,and(19.4±2.3)in HAMA after treatment.Conclusion The modified Chaihu Shugan powder has a better therapeutic effect on hypertension patients with anxiety,can significantly stabilize the blood pressure of patients,while alleviating the anxiety of patients,it is worthy of clinical promotion.