超声造影技术对不同回声颈动脉斑块的应用研究

Application of Contrast-enhanced Ultrasound in Different Echo Carotid Plaques

目的分析超声造影技术(contrast-enhanced ultrasound,CEUS)对不同回声的颈动脉粥样斑块(carotid plaque,CP)的易损性的应用价值。方法将纳入研究的119例患者依次进行常规颈动脉超声及超声造影检查,测量并比较分析不同回声组以及有症状、无症状组CP的大小、增强强度(EI)及增强比率(Ratio)。结果不同回声斑块组间的增强强度比较差异有统计学意义(H=64.671,P<0.001);不同回声斑块组间的增强比率比较差异有统计学意义(H=61.754,P<0.001);有症状组的EI高于无症状组,差异有统计学意义(t=4.114,P<0.001);有症状组的Ratio高于无症状组,差异有统计学意义(t=4.275,P<0.001);有症状组与无症状组之间斑块直径的比较差异无统计学意义(P>0.05)。结论超声造影技术可以对CP的易损性进行量化分析,CP的增强强度、增强比率越高其稳定性越低。

Objective To analyze the value of contrast-enhanced ultrasound(CEUS)in the vulnerability of carotid atherosclerotic plaques with different echo.Methods Routine carotid ultrasound and contrast-enhanced ultrasound were performed on 119 patients enrolled in the study.The size of CP,EI and Ratio were measured and compared between different echo groups and symptomatic and asymptomatic groups.Results There was significant difference in the intensity difference between different echogenic plaque groups(H=64.671,P<0.001).There was significant difference in the contrast ratio among different echogenic plaque groups(H=61.754,P<0.001).The EI of symptomatic group was higher than that of asymptomatic group(t=4.114,P<0.001).The ratio of symptomatic group was higher than that of asymptomatic group(t=4.275,P<0.001).There was no significant difference in the size of plaque between the symptomatic group and the asymptomatic group(P>0.05).Conclusion The vulnerability of CP can be quantitatively analyzed by contrast-enhanced ultrasound.The higher the EI and ratio,the lower the stability.