MRI-DWI联合DCE-MRI在诊断早期强直性脊柱炎活动期骶髂关节中的应用价值

Application Value of Mri in the Differential Diagnosis Between Malignant and Benign Breast Tumor

目的:探讨磁共振弥散加权成像(MRI-DWI)联合多期动态增强扫描(DCE-MRI)在诊断早期强直性脊柱炎活动期骶髂关节中的应用价值。方法:选取我院2016年9月-2018年3月强直性脊柱炎患者90例设为研究组,另选取同期健康体检者90例设为对照组。所有受检者均采取MRI-DWI及DCE-MRI检查,比较两组髂侧及骶侧ADC值、增强斜率(Senh)、增强因子(Fenh)及达到增强后最大信号强度所需时间(Tmax)。结果:研究组髂骶侧ADC值[(5. 04±1. 03)×10^(-4)mm^2/s、(4. 62±0. 68)×10^(-4)mm^2/s]、Senh [(60. 83±37. 45)%min、(43. 89±14. 08)%min]、Fenh[(112. 27±43. 60)%、(83. 11±20. 28)%]高于对照组,Tmax[(114. 33±21. 35) s、(122. 30±27. 41) s]低于对照组(P <0. 05)。结论:MRI-DWI联合DCE-MRI可有效检出强直性脊柱炎患者活动期骶髂关节异常变化,利于为临床及早制定有效干预方案提供一定参考依据。

Objective:To investigate the application value of magnetic resonance imaging(MRI)in the differential diagnosis between malignant and benign breast tumor.Methods:80 patients with breast tumor admitted in the hospital from May 2017 to April 2018 were selected,and they were given CT and MRI examination.The operative and pathological findings were taken as the diagnostic gold standard,the diagnostic accuracy,sensitivity,specificity,positive predictive value,negative predictive value,size of focus of CT and MRI were compared.Results:The postoperative pathological examination showed that 61 cases of the 80 patients were malignant,of which 47 cases were invasive ductal carcinoma,10 cases were intraductal carcinoma,3 cases were invasive lobular carcinoma,and 1 case was mucinous adenocarcinoma;19 cases of the 84 patients were benign,of which 9 cases were fibroadenoma,5 cases werefibrocystic mastopathy,2 cases were intraductal papilloma,2 cases were lobular hyperplasia,and 1 case was internal mammary lymph node;The diagnostic accuracy,sensitivity and negative predictive value of CT were higher than those of MRI(P<0.05);There was statistical difference in the maximum diameter of lesion detected by CT and pathological examination(P<0.05);There was no statistical difference in the maximum diameter of lesion detected by MRI and pathological examination(P>0.05).Conclusion:MRI has higher value in the differential diagnosis of benign and malignant breast tumor.It has higher diagnostic accuracy and sensitivity,and can accurately determine the size of the focus.MRI has important guiding significance in the formulation of clinical treatment plan,which is worthy of clinical promotion and application.