显微外科手术在颅内动脉瘤中的应用效果及对患者应激程度的影响研究

Study on the Application Effect of Microscopic Surgery in the Patients with Intracranial Aneurysm and Influence for the Stress Degree

目的:研究显微外科手术在颅内动脉瘤中的应用效果及对患者应激程度的影响。方法:选取2017年4月-2018年1月笔者所在医院收治的82例颅内动脉瘤患者为研究对象,将其随机分为两组,每组41例。对照组进行血管内介入治疗,观察组则进行显微外科夹闭手术治疗。比较两组患者术后不同时间的GOS评分、手术前后的血清应激激素。结果:观察组术后1周及4周GOS评分优于对照组(P<0.05),由术前至术后1、3 d两组内血清应激激素均先升后降,但两组见差异无统计学意义(P>0.05)。结论:显微外科手术在颅内动脉瘤中的应用效果较好,且对患者的不良应激尚可,故在颅内动脉瘤患者中的应用价值较高。

Objective:To study the application effect of microscopic surgery in the patients with intracranial aneurysm and influence for the stress degree.Method:A total of 82 patients with intracranial aneurysm in hospital from April 2017 to January 2018 were chosen as the research object,and they were randomly into two groups,with 41 cases in each group.The control group were treated with endovascular interventional treatment,the observation group were treated with microsurgical clipping.Then the GOS score at different time after the operation,serum stress hormones before and after the operation of two groups were compared.Result:The GOS score of observation group at first and forth week after the operation were better than those of control group(P<0.05),the serum stress hormones of two groups before the operation and at first and third day after the operation increased first and decreased afterward,while the differences of two groups were not statistically significant(P>0.05).Conclusion:The application effect of microscopic surgery in the patients with intracranial aneurysm is better,and its bad influence for the patients is still available,so its application value in the patients with intracranial aneurysm is higher.