超早期综合康复干预对高危儿神经发育预后的影响

Effect of super early comprehensive rehabilitationon neurodevelopmental prognosis of highrisk infants

目的:观察超早期综合康复干预对早产高危儿神经发育预后的影响。方法:将符合纳入标准的早产高危儿按照家长意愿分为对照组(n=30)和治疗组(n=30)。对照组给予常规治疗,治疗组在对照组的基础上给予综合康复治疗,两组患者疗程均为10日。分别观察两组患儿体重、奶量、NBNA评分、GMFM评分和Gesell评分的变化。结果:治疗组治疗后体重、奶量均较治疗前显著增加(P<0.01),明显优于对照组(P<0.01);治疗组患儿满40周时NBNA评分高于对照组(P<0.05),NBNA异常率低于对照组(P<0.01);治疗组出生后1个月、2个月、3个月A能区和B能区GMFM评分和社会适应、大运动、精细运动、语言和个人社交5个维度均显著增加,明显优于对照组(P<0.05或P<0.01)。结论:超早期综合康复能够改善高危儿的身体素质,促进神经系统的发育,疗效显著。

Objective:To observe the effect of super-early comprehensive rehabilitation intervention on neurodevelopmental prognosis of premature high-risk infants.Methods:Premature high-risk infants who met the inclusion criteria were divided into control group(n=30)and treatment group(n=30)according to parental willingness.The control group was given routine treatment,while the treatment group was treated with comprehensive rehabilitationon the basis of the control group.The course of treatment for both groups was 10 days.The changes of body weight,milk consumption,NBNA score,GMFM score and Gesell score were observed.Results:After treatment,the body weight and milk consumption of the treatment group significantly increased compared with those before treatment(P<0.01),and they weresignificantly better than thoseof the control group(P<0.01);the NBNA score of the treatment group was higher than that of the control group at 40 weeks of gestational age(P<0.05),and the abnormal rate of NBNA was lower than that of the control group(P<0.01).The GMFM scores of A-energy and B-energy areas and the five dimensions of social adaptation,big exercise,fine exercise,language and personal social interactionin the treatment groupsignificantlyincreased in 1 month,2 months and 3 months after birth,which were significantly better than those in the control group(P<0.05 or P<0.01).Conclusion:Super-early comprehensive rehabilitation can improve the physical quality of high-risk infants and promote the development of the nervous system,and the curative effectis remarkable.